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Psychedelic Drug an overview Thus, the psilocybin state is characterized by a larger repertoire of states (i.e., novel motifs that are exclusive to the psychedelic state). Early autoradiographic studies by Jueptner and Weiller indicated that perisynaptic activity, representing primarily input and local processing in the cortex, rather than cell bodies, accounts for the major part of cortical metabolic energy demands. Consistent with that finding, simultaneous measurement of intracortical activity and fMRI in the nonhuman primate has demonstrated that local field potential generated by a local neuronal network is more closely related to the BOLD signal than multiunit activity of the same network (Logothetis et al., 2001). Arvanian et al. carried out a study in which rats received a staggered double hemisection at postnatal day two of the left hemicord at T11 and the right hemicord at T12. A second group had a complete transection at T11 , with a third group serving as a sham-operated